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Circ_0008450 regulated AKAP1 expression by miR-431 in hypoxia-disposed SNU-387 and Huh7 cells. (A and B) Effect of AKAP1 enhancement or (C and D) miR-431 inhibitor on circ_0008450 depletion-mediated expression of AKAP1 mRNA and protein of hypoxia-disposed SNU-387 and Huh7 cells was examined using reverse transcription-quantitative PCR and western blotting. *P<0.05. Circ, circular; AKAP1, A-kinase anchor protein 1; miR, microRNA; si-, small interfering; NC, negative control.
