Table I.

Association between circ_0008450 expression and clinical clinicopathological parameters of patients with hepatocellular cancer.

		circ_0008450 expression
Parameter	Patients, n	Low n=14	High n=16	P-value
Age, years				0.07
≤60	14	9	5
>60	16	5	11
Sex				0.232
Female	18	10	8
Male	12	4	8
Tumor size, cm				0.003a
≤5	17	12	5
>5	13	2	11
TNM stage				0.003a
I–II	15	11	4
III	15	3	12
AFP, µg/l				0.696
≤400	16	8	8
>400	14	6	8
Lymphatic metastasis				0.0001a
Negative	12	11	1
Positive	18	3	15
Vascular invasion				0.961
Absent	13	6	7
Present	17	8	9
Distant metastasis				0.0003a
M0	15	12	3
M1	15	2	13

^aP<0.05 as analyzed by χ² tests. TNM, tumor, node and metastasis staging system; α-fetoprotein tumor marker. M0, HCC was not diffused. M1, HCC had spread to other parts of the body.