TABLE 2.
Logistic regression classifier results tested on an independent sample of participants with mild cognitive impairment (N = 11) prior to conversion to dementia (N = 6)
| Region | Sensitivity | Specificity | Balanced accuracy | AUC |
|---|---|---|---|---|
| Prefrontal | 1.00 | 0.80 | 0.90 | 0.93 |
| Posterior cingulate | 1.00 | 0.60 | 0.80 | 0.83 |
| Inferior parietal | 1.00 | 0.20 | 0.60 | 0.80 |
| Superior frontal | 1.00 | 0.80 | 0.90 | 0.97 |
| Rostral middle frontal | 1.00 | 0.60 | 0.80 | 0.90 |
| Anterior cingulate | 0.83 | 0.80 | 0.82 | 0.90 |
| Superior temporal | 0.83 | 0.40 | 0.62 | 0.67 |
| Middle temporal | 0.83 | 0.40 | 0.62 | 0.80 |
| Brain average | 0.67 | 0.80 | 0.73 | 0.80 |
| Precuneus | 0.67 | 0.40 | 0.53 | 0.73 |
| Lateral Orbitofrontal | 0.67 | 0.80 | 0.73 | 0.77 |
| Medial Orbitofrontal | 0.67 | 0.60 | 0.63 | 0.80 |
| Dorsal striatum | 0.50 | 0.80 | 0.65 | 0.77 |
| Inferior temporal | 0.50 | 0.80 | 0.65 | 0.70 |
| Hippocampus | 0.33 | 1.00 | 0.67 | 0.47 |
| Entorhinal cortex | 0.00 | 1.00 | 0.50 | 0.30 |
| Lateral occipital | 0.00 | 1.00 | 0.50 | 0.67 |
Note: Metrics shown include specificity, sensitivity, accuracy balanced for number of participants in each test group, and area under the receiver operating characteristic curve (AUC).