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MoBaS identified a tightly-interconnected subnetwork involved in cell cycle progression.
(A) The top-scoring protein-protein interaction (PPI) subnetwork in A549, identified from the MoBaS approach. (B) Second top-scoring subnetwork from MoBaS analysis on H358 cells, which enriched for cell cycle proteins. Each node is a phosphoprotein represented by its most significant peptide. Node color is based on log2(fold change) relative to DMSO control.
