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. 2020 Nov 10;10:19470. doi: 10.1038/s41598-020-76591-4

Table 2.

Dominant genera and significant difference between 1-year and 4-years old children.

Genus Feature 1-year: mean rel. freq. (%) 1-year: std. dev. (%) 4-years: mean rel. freq. (%) 4-years: std. dev. (%) q-values Enriched in
Actinomyces Difference 0.1017 0.1187 0.0239 0.0296 0.0021 1-year
Akkermansia Major and difference 0.1368 0.7098 4.6110 13.4165 0.0052 4-years
Alistipes Difference 0.0612 0.2742 0.8799 1.8020 0.0002 4-years
Anaerofustis Difference 0.0006 0.0035 0.0034 0.0091 0.0268 4-years
Anaerotruncus Difference 0.0194 0.0529 0.0750 0.1206 0.0015 4-years
Barnesiella Difference 0.0000 0.0000 0.0307 0.1228 0.0376 4-years
Bifidobacterium Major and difference 22.4657 21.6951 2.4992 4.4353 0.0001 1-year
Bilophila Difference 0.0016 0.0061 0.0827 0.1719 0.0001 4-years
Blautia Major and difference 4.8976 5.9816 2.2828 2.9867 0.0458 1-year
Butyricicoccus Difference 0.0978 0.2197 0.3386 0.5161 0.0011 4-years
Butyricimonas Difference 0.0003 0.0017 0.0185 0.0657 0.0202 4-years
Christensenella Difference 0.0000 0.0000 0.0070 0.0177 0.0009 4-years
Cloacibacillus Difference 0.0000 0.0000 0.0017 0.0063 0.0293 4-years
Clostridium IV Major and difference 0.0136 0.0587 1.8773 3.7870 0.0001 4-years
Clostridium sensu stricto Major and difference 1.9968 3.8008 0.2728 0.6705 0.0324 4-years
Clostridium XlVa Major and difference 0.5308 0.7931 1.1052 1.8900 0.0381 4-years
Clostridium XlVb Difference 0.0067 0.0195 0.4134 0.9732 0.0004 4-years
Clostridium XVIII Major and difference 1.9694 3.7634 0.0981 0.1562 0.0186 1-year
Coprococcus Difference 0.0324 0.1297 0.2113 0.5193 0.0073 4-years
Dialister Major and difference 0.5084 2.8026 4.8636 10.4218 0.0011 4-years
Eggerthella Difference 0.1535 0.2235 0.0381 0.0516 0.0151 1-year
Eisenbergiella Difference 0.0000 0.0000 0.0294 0.0620 0.0001 4-years
Enterococcus Difference 0.2863 0.4723 0.0060 0.0254 0.0051 1-year
Escherichia/Shigella Major and difference 11.9535 14.2319 3.9337 10.4966 0.0126 1-year
Ezakiella Difference 0.0008 0.0038 0.0105 0.0362 0.0284 4-years
Faecalibacterium Major and difference 2.4513 4.7935 10.2261 13.3559 0.0000 4-years
Gemmiger Major and difference 0.7854 2.5049 4.2201 8.4445 0.0018 4-years
Holdemania Difference 0.0177 0.0735 0.0756 0.1338 0.0074 4-years
Hungatella Difference 0.0011 0.0040 0.0110 0.0356 0.0214 4-years
Intestinibacter Major and difference 1.4063 1.6740 0.1925 0.3323 0.0009 1-year
Intestinimonas Difference 0.0000 0.0000 0.0559 0.1416 0.0008 4-years
Klebsiella Major and difference 1.3742 2.7721 0.1372 0.4604 0.0355 1-year
Lactonifactor Difference 0.0008 0.0037 0.0051 0.0116 0.0050 4-years
Odoribacter Difference 0.0000 0.0000 0.0418 0.1476 0.0182 4-years
Oscillibacter Difference 0.0125 0.0326 0.8457 1.0766 0.0000 4-years
Parabacteroides Difference 0.2177 0.5702 0.7776 1.0870 0.0011 4-years
Parasutterella Difference 0.0118 0.0562 0.2985 0.9139 0.0085 4-years
Parvimonas Difference 0.0011 0.0032 0.0058 0.0148 0.0112 4-years
Phascolarctobacterium Difference 0.0089 0.0474 0.7095 1.9686 0.0023 4-years
Pseudoflavonifractor Difference 0.0000 0.0000 0.0011 0.0038 0.0111 4-years
Pyramidobacter Difference 0.0003 0.0017 0.0062 0.0245 0.0454 4-years
Roseburia Major and difference 0.5940 1.6508 4.4477 8.4708 0.0002 4-years
Ruminococcus2 Major and difference 0.3787 0.9090 1.0312 1.6200 0.0144 4-years
Scardovia Difference 0.0000 0.0000 0.0010 0.0040 0.0379 4-years
Streptococcus Major and difference 4.1816 6.7029 0.8335 1.3996 0.0182 1-year
Bacteroides Major 12.9731 19.2120 19.29113 19.1440 0.2184 4-year
Veillonella Major and difference 5.5698 6.5315 1.2074 3.7846 0.0023 1-year