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. 2020 Nov 10;10:19423. doi: 10.1038/s41598-020-76565-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Proportion of β-sheet structures between LBs and GCIs. The white boxes represent mean values, lines represent median values, and the tops and bottoms of the boxes represent the upper and lower limits of the first and third quartiles, respectively. The ends of the whiskers represent maximum and minimum data points. Black dots are individual analysis values. The proportions of the β-sheet structure in LBs and GCIs are 52.6 ± 1.9% (n = 16) and 38.1 ± 0.9% (n = 16) (mean ± the standard error of the mean), respectively. The median values are 53.9% and 37.0%, respectively. Asterisks above the boxes indicate significant differences determined by Student’s t-test (*P < 0.001).