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. 2020 Nov 10;10:19449. doi: 10.1038/s41598-020-76466-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Growth curve of hWJ-MSCs grown on silk scaffold with the following composition: SF 85% + SS 15%, SF 90% + SS 10%, and SF 100% for 1, 3, 5, 7, and 14 days. Between day 5 and day 14, scaffold with the addition of SS 10% was the most optimal to support cell proliferation. ** denotes a significant difference in cell viability (p < 0.005). SF = silk fibroin, SS = silk spidroin.