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. 2020 Jun 1;12(6):1622. doi: 10.3390/nu12061622

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Alpha diversity change of controls and patients before (T0) and after (T1) short-term oral isoflavone intervention. Both the differences of patients (** p = 0.005) and controls (* p = 0.02) between T0 and T1 were significant using Student’s t-tests. There was a significant difference in diversity between controls and PCOS patients in both T0 (* p = 0.023) and T1 (* p = 0.035). However, there was no difference between controls at baseline (T0) and patients after the intervention (T1, ns, p = 0.669). ns p > 0.05, * p < 0.05; ** p < 0.01; *** p < 0.001.