Table 2.
Comparison of sensitivity and specificity estimates for each reference standard category
| Cut-off value | Semi-structured reference standard* | Fully structured reference standard† | MINI reference standard‡ | |||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | |||
| 7 | 0.95 (0.91 to 0.97) | 0.65 (0.58 to 0.71) | 0.95 (0.71 to 0.99) | 0.57 (0.36 to 0.76) | 0.95 (0.89 to 0.98) | 0.60 (0.52 to 0.67) | ||
| 8 | 0.92 (0.87 to 0.95) | 0.72 (0.66 to 0.78) | 0.95 (0.70 to 0.99) | 0.62 (0.41 to 0.80) | 0.91 (0.85 to 0.95) | 0.67 (0.60 to 0.74) | ||
| 9 | 0.89 (0.83 to 0.93) | 0.78 (0.73 to 0.83) | 0.95 (0.64 to 1.00) | 0.71 (0.50 to 0.85) | 0.88 (0.80 to 0.93) | 0.74 (0.66 to 0.80) | ||
| 10 | 0.85 (0.79 to 0.90) | 0.84 (0.79 to 0.88) | 0.93 (0.64 to 0.99) | 0.78 (0.57 to 0.90) | 0.84 (0.74 to 0.91) | 0.79 (0.73 to 0.84) | ||
| 11 | 0.81 (0.75 to 0.87) | 0.88 (0.85 to 0.91) | 0.90 (0.58 to 0.98) | 0.83 (0.62 to 0.94) | 0.82 (0.71 to 0.89) | 0.84 (0.79 to 0.89) | ||
| 12 | 0.75 (0.67 to 0.81) | 0.92 (0.89 to 0.94) | 0.81 (0.56 to 0.94) | 0.86 (0.70 to 0.94) | 0.74 (0.60 to 0.85) | 0.89 (0.83 to 0.92) | ||
| 13 | 0.66 (0.58 to 0.74) | 0.95 (0.92 to 0.96) | 0.79 (0.50 to 0.94) | 0.90 (0.75 to 0.96) | 0.69 (0.54 to 0.81) | 0.91 (0.87 to 0.94) | ||
| 14 | 0.58 (0.50 to 0.66) | 0.96 (0.95 to 0.98) | 0.77 (0.43 to 0.94) | 0.93 (0.82 to 0.98) | 0.60 (0.45 to 0.73) | 0.94 (0.91 to 0.96) | ||
| 15 | 0.51 (0.44 to 0.58) | 0.97 (0.96 to 0.98) | 0.66 (0.37 to 0.87) | 0.95 (0.86 to 0.99) | 0.52 (0.39 to 0.64) | 0.95 (0.92 to 0.97) | ||
MINI=Mini International Neuropsychiatric Interview.
*
Number of studies=36; number of participants=9066; number of participants with major depression=1330.
†
Number of studies=3 for sensitivity and 4 for specificity; number of participants=3188; number of participants with major depression=227. We modified the bivariate model by setting the correlation between random effects to zero and excluded the participant with major depression from the study that had only one participant with major depression.
‡
Number of studies=18; number of participants=3302; number of participants with major depression=511.