Table 3. Comparison of inflammatory indexes among the CAA, CAE, and NCA groups.
| Inflammatory indexes | CAA (n=100) | CAE (n=100) | NCA (n=100) | P | P (pairwise comparison) | ||
|---|---|---|---|---|---|---|---|
| P12 | P23 | P13 | |||||
| CRP level (mg/L) | 6.25±11.10 | 7.45±11.90 | 5.06±14.90 | 0.390 | NA | NA | NA |
| IL-6 level (pg/mL) | 60.63±6.22 | 60.24±2.99 | 59.78±4.78 | 0.464 | NA | NA | NA |
| ET-1 level (pg/mL) | 56.85±6.09 | 59.09±14.40 | 54.75±11.71 | 0.026 | 0.161 | 0.007 | 0.190 |
| MMP-9 level (ng/mL) | 17.93±5.24 | 19.56±6.57 | 16.53±7.81 | 0.006 | 0.152 | 0.010 | 0.364 |
| c-ANCA level (RU/mL) | 1.16±0.48 | 1.35±0.46 | 1.25±0.46 | 0.018 | 0.005 | 0.143 | 0.166 |
| TNF-α level (pg/mL) | 523.72±91.62 | 533.26±130.65 | 493.21±84.84 | 0.019 | 0.518 | 0.007 | 0.040 |
| p-ANCA level (RU/mL) | 1.13±0.37 | 1.16±0.35 | 1.04±0.30 | 0.040 | 0.524 | 0.014 | 0.070 |
| MPO level (ng/mL) | 0.73±0.27 | 0.84±0.25 | 0.69±0.36 | 0.002 | 0.010 | 0.003 | 0.791 |
| GDF-15 level (pg/mL) | 323.78±57.75 | 352.20±105.13 | 308.90±98.54 | 0.003 | 0.026 | 0.001 | 0.241 |
CAA, coronary artery aneurysm; CAE, coronary artery ectasia; NCA, normal coronary artery; CRP, C-reactive protein; IL-6, interleukin-6; ET-1, endothelin-1; MMP-9, matrix metalloproteinase-9; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibody; TNF-α, tumor necrosis factor-α; p-ANCA, perinuclear anti-neutrophil cytoplasmic antibody; MPO, myeloperoxidase; GDF-15, growth/differentiation factor 15; NA, not applicable.