Table S3. Minnesota-Donor-Lung quality index (4).
| Points [possible range of points (0–48)] |
Cohort (N=454) | Univariable Cox regression | ||
|---|---|---|---|---|
| HR; 95% CI | P value | |||
| 1. Anticipated ischemic time | ||||
| <6 hours | 1 | 404 (89.0%) | – | |
| ≥6 hours | 0 | 50 (11.0%) | 1.0; 0.7–1.4 | 0.9 |
| 2. Risk of pneumonia | ||||
| Low | 4 | 173 (38.1%) | – | |
| Moderate | 2 | 232 (51.1%) | 1.0; 0.8–1.2 | 0.9 |
| High | 0 | 49 (10.8%) | 1.1; 1.0–1.1 | 0.2 |
| 3. Donor age | ||||
| 15–45 years | 2 | 234 (51.5%) | – | |
| 46–65 years | 1 | 178 (39.2%) | 1.2; 0.9–1.5 | 0.1 |
| >65 years | 0 | 42 (9.3%) | 1.9; 1.3–2.7 | 0.001 |
| 4. Risk of aspiration injury | ||||
| Low | 3 | 411 (90.5%) | – | |
| Moderate | 2 | 28 (6.2%) | 1.2; 0.8–1.7 | 0.4 |
| High | 0 | 15 (3.3%) | 1.4; 0.7–2.9 | 0.3 |
| 5. Risk of preexisting lung disease | ||||
| Low | 4 | 446 (98.2%) | – | |
| Moderate | 2 | 8 (1.8%) | 1.0; 0.8–1.2 | 0.9 |
| High | 0 | – | – | |
| 6. Risk of pulmonary edema | ||||
| Low | 3 | 447 (98.5%) | – | |
| Moderate | 2 | 7 (1.5%) | 1.7; 0.8–3.7 | 0.1 |
| High | 0 | – | – | |
| 7. Risk of contusion | ||||
| Low | 2 | 428 (94.3%) | – | |
| Moderate | 1 | 15 (3.3%) | 0.7; 0.5–1.2 | 0.2 |
| High | 0 | 11 (2.4%) | 1.0; 0.5–2.0 | 0.9 |
| 8. Blood gasses | ||||
| Good | 3 | 284 (62.6%) | – | |
| Marginal | 0 | 170 (37.4%) | 0.9; 0.9–1.0 | 0.05 |
| 9. Smoking history | ||||
| <30 Pack-years | 2 | 397 (87.4%) | – | |
| ≥30 Pack-years | 0 | 57 (12.8%) | 1.7; 1.2–2.3 | 0.001 |
| 10. Anticipated procurement complexity | ||||
| Simple | 2 | 415 (91.4%) | – | |
| Moderate | 1 | 36 (7.9%) | 1.0; 0.6–1.5 | 0.9 |
| Complex | 0 | 3 (0.7%) | – | |
| 11. Risk of pulmonary malignancy | ||||
| Low | 5 | 283 (62.3%) | – | |
| Moderate | 4 | 94 (20.7%) | 1.1; 0.8–1.4 | 0.7 |
| High | 0 | 77 (17.0%) | 1.6; 1.2–2.1 | 0.001 |
| 12. Risk of donor-transmitted diseases | ||||
| Low | 4 | 452 (99.6%) | – | |
| Moderate | 3 | 2 (0.4%) | – | |
| High | 0 | – | – | |
| 13. Risk of extrapulmonary malignancy | ||||
| Low | 5 | 445 (98.0%) | – | |
| Moderate | 2 | 9 (2.0%) | 0.9; 0.7–1.1 | 0.2 |
| High | 0 | – | ||
| 14. Risk of positive retrospective HLA crossmatch | ||||
| Low | 5 | 454 (100%) | – | |
| Moderate | 3 | – | ||
| High | 0 | – | ||
| 15. Risk of size missmatch | ||||
| Low | 3 | 294 (64.8%) | ||
| Moderate | 2 | 23 (5.1%) | 1.1; 0.9–1.4 | 0.3 |
| High | 0 | 137 (30.2%) | 1.3; 1.0–1.6 | 0.06 |
CI, confidence interval; HLA, human leukocyte antigen; HR, hazard ratio.