Table 1. Baseline demographics and clinical characteristics for patients with high grade (p)T1N0 (≤2 cm) non-small cell lung cancer.
| Parameters | Lobectomy (n=3,977) | Segmentectomy (n=355) | P value | Standardized differences* |
|---|---|---|---|---|
| Age | <0.01 | 0.31 | ||
| Mean/SEM | 67.4/0.143 | 70.2/0.468 | ||
| Sex, n (%) | 0.88 | 0.023 | ||
| Male | 1,888 (47.5) | 167 (47.0) | ||
| Female | 2,089 (52.5) | 188 (53.0) | ||
| Race, n (%) | 0.25 | 0.03 | ||
| White | 3,484 (87.6) | 316 (89.0) | ||
| Black | 294 (7.4) | 28 (7.9) | ||
| Asian | 118 (3.0) | 9 (2.5) | ||
| Other | 81 (2.0) | 2 (0.6) | ||
| Marital status, n (%) | 0.18 | 0.04 | ||
| Single | 427 (10.7) | 39 (11.0) | ||
| Married | 2,232 (56.1) | 184 (51.8) | ||
| Divorced | 540 (13.6) | 45 (12.7) | ||
| Widowed | 587 (14.8) | 71 (20.0) | ||
| Separated | 34 (0.9) | 1 (0.3) | ||
| Unknown | 157 (3.9) | 15 (4.2) | ||
| Tumor location, n (%) | <0.01 | 0.18 | ||
| Right upper lobe | 1,584 (39.8) | 113 (31.8) | ||
| Right middle lobe | 248 (6.2) | 5 (1.4) | ||
| Right lower lobe | 574 (14.4) | 57 (16.1) | ||
| Left upper lobe | 1,057 (26.6) | 112 (31.5) | ||
| Left lower lobe | 514 (12.9) | 68 (19.2) | ||
| Tumor histology, n (%) | 0.18 | 0.03 | ||
| Squamous cell carcinoma | 1,424 (35.8) | 132 (37.2) | ||
| Adenocarcinoma | 1,887 (47.4) | 160 (45.1) | ||
| Large cell carcinoma | 222 (5.6) | 25 (7.0) | ||
| Neuroendocrine | 36 (0.9) | 7 (2.0) | ||
| Other | 408 (10.3) | 31 (8.7) | ||
| Tumor grade, n (%) | 0.39 | 0.01 | ||
| Poorly differentiated, grade III | 3,813 (95.9) | 337 (94.9) | ||
| Undifferentiated, grade IV | 164 (4.1) | 18 (5.1) | ||
| (p) T stage, n (%) | <0.01 | |||
| (p)T1a | 530 (13.3) | 66 (18.6) | ||
| (p)T1b | 3,447 (86.7) | 289 (81.4) | ||
| Tumor size (mm) | 0.04 | –0.17 | ||
| Mean/SEM | 15.3/0.059 | 14.7/0.212 | ||
| Number of lymph nodes | <0.01 | |||
| Mean/SEM | 8.81/0.124 | 4.35/0.303 |
*, Standardized differences only presented for preoperative variables, used in propensity score analysis. SEM, standard error of the mean.