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. 2020 Nov 11;20:340. doi: 10.1186/s12906-020-03132-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Effect of HESAE on endogenous antioxidant enzyme activities in PC-12 cells treated with high-dose corticosterone. a SOD, b CAT and c GPx activities were evaluated by SOD, CAT and GPx assays following pre-treatment with HESAE for 48 h and high-dose corticosterone of 400 μM for 24 h. Data are expressed as mean ± SD and statistically analysed by Tukey’s test. Asterisks (*) and hash signs (#) indicate significant differences (p < 0.05) in SOD, CAT and GPx activities compared to the corticosterone group and desipramine group, respectively