Table 2.
Hazard ratio of cardiovascular outcomes in patients with acute coronary syndrome by diabetes status
| Without diabetes (n = 2989) | With diabetes (n = 3989) | Unadjusted HR (95% CI) | Adjusted HR (95% CI)a | |||||
|---|---|---|---|---|---|---|---|---|
| Person-years | No. of events | Event rate (per 100 PY) | Person-years | No. of events | Event rate (per 100 PY) | |||
| MACE | 13,057 | 524 | 4.01 | 19,096 | 1109 | 5.81 | 1.49 (1.34–1.65) | 1.22 (1.09–1.37) |
| Cardiovascular death | 14,471 | 153 | 1.06 | 22,913 | 286 | 1.25 | 1.25 (1.03–1.53) | 1.15 (0.92–1.43) |
| Myocardial infarction | 13,542 | 272 | 2.01 | 20,734 | 500 | 2.41 | 1.26 (1.09–1.50) | 1.05 (0.89–1.23) |
| Stroke | 13,863 | 196 | 1.41 | 20,812 | 592 | 2.84 | 2.06 (1.75–2.42) | 1.50 (1.26–1.79) |
| Hospitalization for heart failure | 14,103 | 162 | 1.15 | 21,385 | 513 | 2.40 | 2.13 (1.79–2.55) | 1.47 (1.22–1.78) |
| All-cause death | 14,471 | 325 | 2.25 | 22,913 | 698 | 3.05 | 1.40 (1.23–1.60) | 1.28 (1.11–1.49) |
CI confidence interval, HR hazard ratio, MACE major adverse cardiovascular events, PY person-years
aAdjusted for sex, age, body mass index, systolic blood pressure, fasting glucose, total cholesterol, alcohol consumption, smoking status, physical activity, household income, concurrent medications, comorbidities, and index year