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. 2020 Nov 10;20:1087. doi: 10.1186/s12885-020-07503-y

Table 4.

Attrition rates by LOT

LOT Frequency, N Attrition, % Deaths, n (%) No subsequent treatment in follow-up, n (%) Subsequent treatment, n (%) Mean ± SD treatment duration, months (median)
Non-transplant
 1 22,062 2841 (12.9) 9716 (44.0) 9505 (43.1) 6.9 ± 9.6 (3.6)
 2 9505 56.9 1155 (12.2) 3168 (33.3) 5182 (54.5) 7.5 ± 9.5 (4.1)
 3 5182 45.5 636 (12.3) 1575 (30.3) 2971 (57.3) 6.5 ± 8.0 (3.7)
 4 2971 42.7 364 (12.3) 901 (30.3) 1706 (57.4) 5.7 ± 6.6 (3.4)
 5 1706 42.6 209 (12.3) 508 (29.8) 989 (58.0) 5.5 ± 6.4 (3.2)
Transplant
 1 2763 36 (1.3) 543 (19.6) 2184 (79.0) 6.3 ± 8.0 (4.2)
 2 2184 21.0 60 (2.7) 613 (28.1) 1511 (69.2) 6.1 ± 9.2 (2.7)
 3 1511 30.8 63 (4.2) 494 (32.7) 954 (63.1) 7.4 ± 9.8 (3.6)
 4 954 36.9 60 (6.3) 276 (28.9) 618 (64.8) 6.6 ± 9.4 (3.4)
 5 618 35.2 49 (7.9) 180 (29.1) 389 (62.9) 5.6 ± 6.2 (3.3)

LOT Line of therapy, SD Standard deviation