Skip to main content
. 2020 Sep 24;41(11):1416–1426. doi: 10.1038/s41401-020-00517-z

Fig. 7. αGC-induced acceleration of progressive ISO stimulation-induced cardiac fibrosis was partly reversed by an IL-6 neutralizing antibody.

Fig. 7

WT C57BL/6 mice received ISO (5 mg/kg per day) alone for 7 days or together with αGC (3 μg/mouse) every other day following IL-6 neutralizing antibody (50 μg/mouse) pretreatment. a HE staining and Masson’s trichrome staining were performed, and the ratio of heart weight to body weight (b) and fibrotic area/LV percentage (c) were calculated. The data are expressed as the mean ± SD. *P < 0.05 and **P < 0.01