Table 2.

Molecular characterization and age of cases with gene fusions in AML and MDS

	Cases with novel fusions only	Cases with known fusions	Cases with no detected fusion
AML
TP53 mutations	67*	1	9
Complex karyotype	71*	1	9
FLT3-ITD	0	13	24
NPM1 mutations	8	0	35
RUNX1 mutations	8	2	12
CEBPA mutations (biallelic)	0	0	5
Median age, y	72	54*	70
MDS
TP53 mutations	26*	0	6
Complex karyotype	21*	0	1
Median age, y	67	46	73

Data are percentages unless otherwise noted.

*Significant differences.