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. 2020 Nov 9;4(21):5527–5539. doi: 10.1182/bloodadvances.2020001658

Table 3.

Crude and adjusted marginal means or effects of studied factors on EEV and PEV Counts

Variable EEVs (n = 631) PEVs (n = 632)
Crude Adjusted* † Crude Adjusted
Mean/effect 95% CI P Mean/effect 95% CI P Mean/effect 95% CI P Mean/effect 95% CI P
Processing factors
 Filter <.0001 <.0001
  Fe-WBf 477.3 (324.5 to 630.0) 73.4 (–310.3 to 457.1)
  M-WBf 1098.2 (861.4 to 1329.8) 16.0 (–767.5 to 799.4)
  Fr-WBf 1095.6 (786.3 to 1410.0) 4555.3 (3967.0 to 5143.5)
  M-RBCf 129.4 (–456.8 to 715.6) 33.5 (–1439.2 to 1506.2)
  Fe-RBCf 438.9 (299.4 to 578.4) 25.1 (–325.3 to 375.5)
 Preparation time, h 36.8 (18.2 to 55.5) <.001 25.4 (6.2 to 44.6) .01 119.2 (67.5 to 171.0) <.0001
Product factors
 Storage time, d 45.5 (35.8 to 55.3) <.0001 42.4 (27.9 to 56.9) <.0001 5.4 (–23.5 to 34.2) .7146
 Erythrocyte count, ×1012/L 75.6 (–80.0 to 231.1) .34 −381.2 (–815.0 to 52.6) .0849
 Platelet count, ×109/L 6.2 (3.0 to 9.5) <.001 67.1 (59.7 to 74.6) <.0001 67.1 (59.7 to 74.6) <.0001
 Volume, mL 3.7 (–0.5 to 7.9) .08 16.1 (4.5 to 27.6) .0067
Donor factors
 Donor age, y −1.3 (–7.5 to 5.0) .69 6.9 (–10.5 to 24.3) .44
 Donor sex .20 .01
  Female 671.5 (523.0 to 820.0) 1128.3 (716.0 to 1540.6)
  Male 547.4 (431.7 to 663.1) 435.6 (114.6 to 756.7)
 Blood group <.0001 <.001
  O 509.7 (378.0 to 641.4) 638.2 (270.0 to 1006.3)
  A 558.3 (426.2 to 690.5) 439.1 (69.7 to 808.5)
  B 1273.8 (911.9 to 1635.7) 2748.4 (1736.8 to 3760.0)
  AB 1897.3 (1032.1 to 2762.5) 2574.4 (156.2 to 4992.6)
  Rh(D) .48 .68
  Positive 607.2 (595.1 to 705.4) 444.8 (718.4 to 992.0)
  Negative 510.4 (333.4 to 759.9) −135.6 (559.8 to 1255.2)
 Erythrocyte count, ×1012/L 224.8 (–16.1 to 465.6) .07 264.9 (40.4 to 489.4) .02 −712.8 (–1383.5 to −42.1) .04
 White blood cell count, ×109/L 6.0 (–47.3 to 59.3) .83 97.0 (–51.4 to 245.3) .20

Data are reported as mean (95% CI): marginal or predicted means for categorical variables and the predicted effect for a 1-unit change of the covariate for quantitative variables.

*

Interaction term between product platelet count and filter type was significant (P = .0003). Platelet count effect for filter type RZ2000, 126.6; LXT, 178.4; Fr, −104.8; NPT, 62.1; and OptiPure, 6.0.

Interaction term between donor blood group and storage time was significant (P = .0003). Storage time effect for blood group O, 0; A, −6.3; B, 27.3; and AB, 58.0.