Table 6.

The individual input symptoms that best explained the diagnoses based on adjusted R-squared: major depressive episodes, dysthymic disorder and manic episodes by assumed input symptom prevalence and correlations

Assumed correlations between input symptoms	Assumed prevalence of input symptoms	Major depressive episodes	Dysthymic disorder	Manic episodes
0	0.05	mde_ma1	dys_ma	man_ma3
0	0.05	0.001 (95% CI 0.001 to 0.001)	0.076 (95% CI 0.075 to 0.077)	0.002 (95% CI 0.002 to 0.002)
0	0.1	mde_ma1	dys_ma	man_ma3
0	0.1	0.01 (95% CI 0.01 to 0.01)	0.228 (95% CI 0.227 to 0.229)	0.021 (95% CI 0.02 to 0.021)
0	0.3	mde_ma1	dys_ma	man_ma3
0	0.3	0.167 (95% CI 0.167 to 0.167)	0.774 (95% CI 0.773 to 0.774)	0.366 (95% CI 0.366 to 0.367)
0	0.5	mde_ma2	dys_ma	man_ma3
0	0.5	0.324 (95% CI 0.324 to 0.325)	0.971 (95% CI 0.971 to 0.971)	0.773 (95% CI 0.772 to 0.773)
0	0.7	mde_ma2	dys_ma	man_ma3
0	0.7	0.412 (95% CI 0.412 to 0.412)	0.999 (95% CI 0.999 to 0.999)	0.964 (95% CI 0.964 to 0.964)
0.1	0.05	mde_ma2	dys_ma	man_ma3
0.1	0.05	0.07 (95% CI 0.07 to 0.071)	0.353 (95% CI 0.352 to 0.355)	0.136 (95% CI 0.135 to 0.137)
0.1	0.1	mde_ma1	dys_ma	man_ma3
0.1	0.1	0.101 (95% CI 0.1 to 0.101)	0.462 (95% CI 0.461 to 0.463)	0.199 (95% CI 0.198 to 0.199)
0.1	0.3	mde_ma2	dys_ma	man_ma3
0.1	0.3	0.242 (95% CI 0.242 to 0.243)	0.777 (95% CI 0.777 to 0.778)	0.483 (95% CI 0.483 to 0.484)
0.1	0.5	mde_ma2	dys_ma	man_ma3
0.1	0.5	0.365 (95% CI 0.365 to 0.366)	0.932 (95% CI 0.931 to 0.932)	0.74 (95% CI 0.74 to 0.741)
0.1	0.7	mde_ma2	dys_ma	man_ma3
0.1	0.7	0.445 (95% CI 0.445 to 0.446)	0.986 (95% CI 0.986 to 0.986)	0.906 (95% CI 0.906 to 0.907)
0.4	0.05	mde_ma1	dys_ma	man_ma3
0.4	0.05	0.375 (95% CI 0.373 to 0.376)	0.731 (95% CI 0.729 to 0.732)	0.561 (95% CI 0.559 to 0.562)
0.4	0.1	mde_ma1	dys_ma	man_ma3
0.4	0.1	0.395 (95% CI 0.394 to 0.396)	0.763 (95% CI 0.762 to 0.764)	0.595 (95% CI 0.594 to 0.596)
0.4	0.3	mde_ma1	dys_ma	man_ma3
0.4	0.3	0.465 (95% CI 0.465 to 0.466)	0.851 (95% CI 0.85 to 0.851)	0.701 (95% CI 0.701 to 0.702)
0.4	0.5	mde_ma2	dys_ma	man_ma3
0.4	0.5	0.525 (95% CI 0.524 to 0.525)	0.908 (95% CI 0.908 to 0.908)	0.787 (95% CI 0.786 to 0.787)
0.4	0.7	mde_ma2	dys_ma	man_ma3
0.4	0.7	0.568 (95% CI 0.568 to 0.569)	0.946 (95% CI 0.946 to 0.947)	0.855 (95% CI 0.854 to 0.855)
0.7	0.05	mde_ma2	dys_ma	man_ma3
0.7	0.05	0.688 (95% CI 0.687 to 0.69)	0.909 (95% CI 0.908 to 0.909)	0.831 (95% CI 0.83 to 0.832)
0.7	0.1	mde_ma1	dys_ma	man_ma3
0.7	0.1	0.688 (95% CI 0.687 to 0.689)	0.912 (95% CI 0.911 to 0.913)	0.836 (95% CI 0.835 to 0.836)
0.7	0.3	mde_ma2	dys_ma	man_ma3
0.7	0.3	0.71 (95% CI 0.709 to 0.711)	0.93 (95% CI 0.93 to 0.93)	0.862 (95% CI 0.861 to 0.862)
0.7	0.5	mde_ma2	dys_ma	man_ma3
0.7	0.5	0.729 (95% CI 0.728 to 0.729)	0.944 (95% CI 0.943 to 0.944)	0.882 (95% CI 0.882 to 0.883)
0.7	0.7	mde_ma1	dys_ma	man_ma3
0.7	0.7	0.745 (95% CI 0.744 to 0.745)	0.954 (95% CI 0.954 to 0.955)	0.9 (95% CI 0.9 to 0.9)
0.9	0.05	mde_ma1	dys_ma	man_ma3
0.9	0.05	0.828 (95% CI 0.827 to 0.829)	0.958 (95% CI 0.957 to 0.958)	0.918 (95% CI 0.917 to 0.919)
0.9	0.1	mde_ma2	dys_ma	man_ma3
0.9	0.1	0.838 (95% CI 0.838 to 0.839)	0.961 (95% CI 0.961 to 0.961)	0.925 (95% CI 0.924 to 0.925)
0.9	0.3	mde_ma2	dys_ma	man_ma3
0.9	0.3	0.856 (95% CI 0.856 to 0.857)	0.969 (95% CI 0.968 to 0.969)	0.937 (95% CI 0.936 to 0.937)
0.9	0.5	mde_ma2	dys_ma	man_ma3
0.9	0.5	0.862 (95% CI 0.862 to 0.863)	0.972 (95% CI 0.972 to 0.972)	0.942 (95% CI 0.942 to 0.943)
0.9	0.7	mde_ma2	dys_ma	man_ma3
0.9	0.7	0.865 (95% CI 0.865 to 0.866)	0.974 (95% CI 0.974 to 0.974)	0.946 (95% CI 0.946 to 0.946)

See table 2 to 4 for variable definitions. Adjusted R-squared is derived from linear regressions using individual input symptoms as predictor with 95% confidence intervals (CIs) derived from 100 simulations for each combination of assumed input symptom prevalence and correlations.

CI, confidence interval.