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. 2020 Nov 6;15:8697–8715. doi: 10.2147/IJN.S274459

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© 2020 Yang et al.

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Morphology, patency, functionality, and mechanical properties of vascular grafts. PU/fibrin (15:85) vascular grafts were transplanted into the abdominal aorta of SD rats for 1, 2, and 3 months and the red arrows represented the distal and proximal locations of the graft (A). The PU/fibrin (15:85) neoarteries at 3 months were washed with PBS solution and the red arrows represented the distal and proximal locations of the graft (B). The cross-section images of the PU/fibrin (15:85) graft observed by stereo microscope (C). Quantitative data were used to analyze the viability and patency performance of vascular grafts in vivo (D and E). Constriction response of different samples under the action of KCL and AD (F). Ach and SNP were used to evaluate the relaxation response of different vascular grafts (G) (n=3). The elastic modulus (H), breaking strain (I) and maximum stress (J) of different vascular grafts were evaluated, respectively (n=3). The compliance of PU/fibrin vascular grafts was measured at 1, 2 and 3 months (K). Scale bar: 1mm. _★ indicated P < 0.05.