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. 2020 Oct 28;10:574679. doi: 10.3389/fonc.2020.574679

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Copyright © 2020 Obara, Blonski, Brzenczek, Mézières, Gaudeau, Pouget, Gauchotte, Verger, Vogin, Moureaux, Duffau, Rech and Taillandier

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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First-line therapeutic strategy and its evolution over time. (A) The median time delay is presented for both groups: patients who were early treated and delayed treated. The width of the arrows is proportional to the percentage of patients that have received the different treatments. (B) Change of first-line therapeutic strategy over time. S, surgery; CT, chemotherapy; RT, radiotherapy.