Table 1.

Neursological manifestations found in COVID-19 research studies

Study type	Origin of study	Other manifestations	Neurological drawbacks	References
Letter to the editor	Switzerland	-Taste and/or smell loss may be observed following SARS-CoV-2 infection. - Observations suggested that the transient anosmia can be recovered following several weeks along with a probability that the impairment remains irreversible.	- Olfactory epithelium bulb can serve as a direct pathway for COVID-19 to penetrate the brain via the nose.	[36]
Review	Liverpool, UK	- Fever and respiratory distress syndrome were observed during the first 14 days of infection.	- Observed neurological manifestations following COVID-19 viral infection which was detected in the CSF followed by neck stiffness, headache, seizures, neuro-muscular disease, motor neuropathy, myopathy, intracerebral hemorrhages, and dementia neurocognitive Syndrome.	[37]
Case report	Japan	- Fever, fatigue, headache, fever, and sore throat.	- Covid-19 was found to be negative in nasopharyngeal swab and positive in CSF. - Seizures and loss of consciousness were clinically observed.	[38]
Case report	China	-Fever and dry cough were observed in the first few days following neurological symptoms along with fatigue and areflexia.	- Positive COVID-19 in the oropharyngeal swab. -Several Neurological complications were clinically observed including inflammatory demyelinating polyneuropathy.	[39]
Case report	USA	- Respiratory distress syndrome with altered mental and elevated CRP.	- Seizures accompanied by exaggerated cytokines release.	[40]
Perspective	China	- No observed clinical symptoms including fever and cough fever with no shortness of breath except on physical activities.	- Several neurological manifestations were observed including headache, dizziness, mild cognitive impairment, blurred vision, and musculoskeletal damage.	[41]
Letter to the editor	USA	- Fever, cough, and shortness of breath.	- Dizziness, headache, altered mental status, nerve pain, and acute cerebrovascular disease were clinically observed along with dementia in some cases.	[42]