Table 4.

Cytokine concentrations from lung homogenate of infected mice at day 7 and day 14 post-infection according to infecting Cryptococcus neoformans MLST group.

		Mean cytokine concentration (pg per gram of lung tissue) [95%CI]
Cytokine		ST5	Non-ST5	*P value (ST5 vs non-ST5)
Day 7
Th-1	IL-12	853.12	822.87	.30
		[750.50–955.80]	[608.90–1037.00]
	IFN-γ	136.02	150.59	.97
		[115.00–157.00]	[105.80–195.30]
	TNF-α	3933.71	3256.25	.01
		[3486.00–4381.00]	[2630.00–3882.00]
Th-2	IL-4	230.79	253.24	.92
		[162.80–298.80]	[11.60–349.90]
	IL-5	561.05	459.85	.91
		[369.00–753.10]	[344.40–575.40]
	IL-10	145.01	139.99	.68
		[128.20–161.80]	[119.30–160.70]
Th-17	IL-17	268.48	243.41	.24
		[155.90–381.00]	[165.60–321.20]
TNF-α/IL-10 ratio		27.13	23.26	ND
Day 14
Th-1	IL-12	547.84	213.72	<.01
		[412.40–683.30]	[120.50–306.90]
	IFN-γ	91.2	1760.67	.09
		[57.25–125.20]	[166.50–3355.00]
	TNF-α	2802.36	6378.76	<.01
		[2385.00–3220.00]	[3374.00–9384.00]
Th-2	IL-4	1154.72	800.35	.60
		[673.50–636.00]	[604.70–996.00]
	IL-5	294.6	347.55	.15
		[170.40–418.80]	[279.20–415.90]
	IL-10	132.76	220.15	.01
		[102.10–163.40]	[172.40–267.90]
Th-17	IL-17	175.75	1012.49	.01
		[65.54–286.00]	[459.20–1566.00]
TNF-α/IL-10 ratio	21.11	28.97	ND

*Mann-Whitney test. ND = not done.