Table 2.
Six cytokines that differed significantly between esophageal squamous cell carcinoma patients whose histological response to preoperative chemoradiotherapy was graded G3, and those whose response was graded G1/2
| Cytokines | G1 and G2 (n = 30) | G3 (n = 7) | P‐value* | ||
|---|---|---|---|---|---|
| Average (pg/mL) | SEM | Average (pg/mL) | SEM | ||
| MIP1B | 84.7 | 10.1 | 40.3 | 8.3 | 0.002 |
| sIL6R | 22528.6 | 1210.6 | 16520.7 | 1432.4 | 0.005 |
| MIP1A | 31.7 | 7.8 | 9.2 | 5.6 | 0.027 |
| Insulin | 2.1 | 0.6 | 0.6 | 0.0 | 0.031 |
| IFNA2 | 386.1 | 172.6 | 25.7 | 25.5 | 0.048 |
| MMP3 | 46396.2 | 5057.2 | 34817.6 | 2565.2 | 0.049 |
Histological responses graded according to the Japanese Classification of Esophageal Cancer (9th edition). *P‐values were calculated using Student's t‐test. INFA2, interferon‐α2; MIP1A, macrophage inflammatory protein α1; MIP1B, macrophage inflammatory protein 1‐β; SEM, standard error of the mean; sIL6R, soluble interleukin‐6 receptor.