Figure 1.

Suppression of vascular endothelial growth factor (VEGF)‐C‐driven lymphatic endothelial cell (LEC) proliferation by conditioned medium of soluble vascular endothelial growth factor receptor‐3 (sVEGFR‐3)‐expressing cells. Cells were plated at 5 × 10³ cells/well in 96‐well plates, and 50% sVEGFR‐3‐conditioned medium or luciferase‐conditioned medium was added with 100 ng/mL recombinant human VEGF‐C. The number of LEC with 50% sVEGFR‐3‐conditioned medium (b) was clearly smaller than that with control (a). The cells were counted by colorimetric assay 48 h after plating. Each bar represents the mean ± SD. (*P < 0.01) (c).