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. 2013 Mar 15;104(5):639–646. doi: 10.1111/cas.12121

Figure 3.

Figure 3

Survival curves according to Ki‐67 and androgen receptor (AR)−/5α‐reductase type 1 (5αR1)− status of breast cancer patients. Kaplan–Meier survival curves analyzed according to 5αaR1‐/AR‐ (a) and Ki‐67 labeling index (LI) (b). Double negative cases were tentatively defined as having less than 10% LI for AR and less than 50% of carcinoma areas immunohistochemically positive for 5αR1. Low Ki‐67 cases were tentatively defined as less than 25% Ki‐67 LI, with high Ki‐67 cases greater than 25% LI (median value). Survival curves and analysis were truncated at 80 months because this was the longest time to follow up in the Thai cohort. If not truncated the survival curve of androgen action negative groups the patients crossed at approximately 90 months, but the Ki‐67 survival curves did not cross until 150 months (the longest time of clinical follow‐up in this study).