Table 2.
Factor (risk indicator) | Recurrence‐free survival (n = 169) | Overall survival (n = 206) | ||||||
---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |||||
HR (95% CI) | P‐value | HR (95% CI) | P‐value | HR (95% CI) | P‐value | HR (95% CI) | P‐value | |
Age (>60 years) | 1.66 (0.86–3.19) | 0.129 | – | – | 0.97 (0.59–1.58) | 0.895 | – | – |
Gender (male) | 1.40 (0.78–2.51) | 0.260 | – | – | 2.48 (0.91–2.40) | 0.116 | – | – |
Location (rectum) | 1.22 (0.69–2.15) | 0.488 | – | – | 1.05 (0.66–1.68) | 0.830 | – | – |
Tumor grade (poor) | 2.66 (1.05–6.73) | 0.039 | 4.62 (1.66–12.84) | 0.003 | 2.09 (0.90–4.83) | 0.085 | 2.58 (1.03–6.45) | 0.042 |
Tumor depth (pT4) | 1.98 (1.11–3.56) | 0.022 | 1.31 (0.69–2.46) | 0.408 | 2.82 (1.76–4.50) | <0.001 | 2.07 (1.25–3.41) | 0.004 |
Node (positive) | 3.07 (1.71–5.51) | <0.001 | 2.22 (1.20–4.09) | 0.011 | 3.07 (1.85–5.09) | <0.001 | 2.15 (1.27–3.65) | 0.005 |
MUC1 (high) | 2.41 (1.23–4.72) | 0.011 | 2.23 (1.10–4.50) | 0.026 | 2.35 (1.35–4.12) | 0.003 | 2.27 (1.25–4.13) | 0.007 |
MUC2(low) | 1.94 (0.99–3.80) | 0.054 | 1.92 (0.92–3.98) | 0.082 | 1.82 (1.04–3.18) | 0.036 | 1.51 (0.83–2.72) | 0.177 |
MUC4 (high) | 2.55 (1.45–4.50) | 0.001 | 2.30 (1.21–4.36) | 0.011 | 2.24 (1.40–3.58) | 0.001 | 1.51 (0.91–2.53) | 0.114 |
MUC5 (negative) | 1.76 (0.93–3.33) | 0.082 | 1.89 (0.95–3.74) | 0.070 | 1.74 (1.01–3.01) | 0.046 | 1.65 (0.93–2.92) | 0.087 |
Values in bold indicate P < 0.05. –, not applicable; CI, confidence interval; HR, hazard ratio.