Table 2.
Relation between intratumoral β1, 6‐N‐acetylglucosaminyltransferase V (MGAT5) expression and clinical characteristics in three independent sets of patients with gastric cancer
Factor | Training set | Testing set | Validation set | ||||||
---|---|---|---|---|---|---|---|---|---|
MGAT5 expression | MGAT5 expression | MGAT5 expression | |||||||
High | Low | P | High | Low | P | High | Low | P | |
All patients | 44 | 53 | 61 | 65 | 35 | 55 | |||
Age, years† | 0.321 | 0.802 | 0.682 | ||||||
≤63 | 23 | 33 | 24 | 27 | 15 | 26 | |||
>63 | 21 | 20 | 37 | 38 | 20 | 29 | |||
Gender | 0.426 | 0.973 | 0.640 | ||||||
Female | 14 | 21 | 18 | 19 | 8 | 15 | |||
Male | 30 | 32 | 43 | 46 | 27 | 40 | |||
Localization | 0.799 | 0.076 | 0.611 | ||||||
Proximal | 4 | 6 | 18 | 10 | 9 | 16 | |||
Middle | 22 | 23 | 18 | 30 | 9 | 18 | |||
Distal | 18 | 24 | 25 | 25 | 17 | 21 | |||
Differentiation | 0.030 | <0.001 | <0.001 | ||||||
Well | 3 | 2 | 13 | 4 | 1 | 0 | |||
Moderate | 22 | 14 | 23 | 11 | 22 | 14 | |||
Poor | 19 | 37 | 25 | 50 | 12 | 41 | |||
Lauren classification | 0.198 | 0.002 | 0.001 | ||||||
Intestinal type | 35 | 36 | 50 | 37 | 31 | 30 | |||
Diffuse type | 9 | 17 | 11 | 28 | 4 | 25 | |||
T classification | 0.013 | 0.153 | 0.195 | ||||||
T1 | 18 | 8 | 7 | 3 | 3 | 1 | |||
T2 | 6 | 4 | 8 | 4 | 3 | 5 | |||
T3 | 1 | 3 | 8 | 6 | 5 | 3 | |||
T4 | 19 | 38 | 38 | 52 | 24 | 46 | |||
N classification | 0.009 | 0.004 | 0.042 | ||||||
N0 | 25 | 13 | 28 | 14 | 13 | 7 | |||
N1 | 6 | 13 | 7 | 7 | 6 | 10 | |||
N2 | 6 | 8 | 12 | 10 | 9 | 17 | |||
N3 | 7 | 19 | 14 | 34 | 7 | 21 | |||
Distant metastasis | 0.311 | 0.504 | 0.422 | ||||||
No | 44 | 50 | 61 | 63 | 35 | 52 | |||
Yes | 0 | 3 | 0 | 2 | 0 | 3 | |||
TNM stage | 0.006 | 0.014 | 0.004 | ||||||
I | 21 | 9 | 12 | 5 | 5 | 1 | |||
II | 8 | 11 | 20 | 12 | 13 | 10 | |||
III | 15 | 30 | 29 | 46 | 17 | 41 | |||
IV | 0 | 3 | 0 | 2 | 0 | 3 | |||
Tumor size, cm† | 0.137 | 0.576 | 0.248 | ||||||
<3.5 | 29 | 27 | 27 | 32 | 10 | 10 | |||
≥3.5 | 15 | 26 | 34 | 33 | 25 | 45 | |||
Kiel stage | 0.026 | 0.003 | 0.013 | ||||||
I | 16 | 5 | 6 | 1 | 2 | 0 | |||
II | 9 | 8 | 21 | 12 | 11 | 6 | |||
IIIA | 2 | 5 | 2 | 3 | 4 | 3 | |||
IIIB | 11 | 16 | 21 | 18 | 11 | 26 | |||
IV | 6 | 19 | 11 | 31 | 7 | 20 |
Kiel stage, Kiel proposal of stage grouping. †Split at median.