Table 4.

Results of the connectivity scoring analysis using our database

Rank	Compound name	Connectivity score	Up score	Down score
(a) Trichostatin A (up, 232; down, 181)
1	Trichostatin A	1.000	0.992	−0.994
2	Vorinostat	0.992	0.987	−0.984
3	Vorinostat	0.976	0.976	−0.964
4	Vorinostat (16 h)	0.921	0.924	−0.906
5	Vorinostat (16 h)	0.906	0.905	−0.893
6	PP242	0.672	0.693	−0.642
7	Doxorubicin	0.667	0.552	−0.773
8	Etoposide (16 h)	0.661	0.732	−0.581
9	Gemicitabine (16 h)	0.658	0.717	−0.591
10	Neocarzinostatin (16 h)	0.647	0.688	−0.597
(b) Vorinostat (up, 233; down, 173)
1	Vorinostat	1.000	0.992	−0.994
2	Trichostatin A	0.988	0.981	−0.982
3	Vorinostat	0.970	0.963	−0.963
4	Vorinostat (16 h)	0.925	0.925	−0.912
5	Vorinostat (16 h)	0.916	0.918	−0.900
6	PP242	0.684	0.698	−0.660
7	Etoposide (16 h)	0.675	0.745	−0.597
8	Doxorubicin	0.658	0.555	−0.752
9	Neocarzinostatin (16 h)	0.658	0.715	−0.591
10	Gemicitabine (16 h)	0.654	0.726	−0.573

The number of up‐ and down‐signatures are shown in parentheses.