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. 2013 May 27;104(7):912–919. doi: 10.1111/cas.12172

Table 8.

Pharmacokinetic parameters of melphalan and prednisolone administered as part of VMP therapy

PK parameter Melphalan (n = 11) Prednisolone (n = 14)
Mean SD Mean SD
C max (ng/mL) 100.200 49.5150 1131.000 223.9200
t max (h) 1.513 0.6049 2.503 1.2429
AUC last (ng·h/mL) 185.600 84.9200 7643.700 2304.7000

AUC last, area under the plasma concentration‐time curve from time zero to the last quantifiable time; C max, maximum plasma concentration; PK, pharmacokinetic; t max, time to reach the maximum plasma concentration.