Table 3.
Toxicity grades | Clinical trial | Total (%) | |
---|---|---|---|
Phase I tria† | DTX consolidation‡ | ||
Without late toxicity | 10 | 62 | 72 (64) |
Grade 1 | 4 | 14 | 18 (16) |
Grade 2 | 3 | 12 | 15 (13) |
Grade 3 | 1 | 2 | 3 (3) |
Grade 4 | 0 | 0 | 0 |
Grade 5¶ | 0 | 4 | 4 (4) |
†The phase I study of concurrent thoracic radiotherapy with cisplatin plus vinorelbine. ‡The docetaxel consolidation therapy following concurrent chemoradiotherapy study. §Late toxicities were defined as those that occurred or persisted 90 days after completion of radiotherapy. ¶The Grade 5 pulmonary toxicities developed at 4.4, 5.9, 9.4, and 9.6 months after the treatment started.