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Bioluminescent imaging of conditionally replicative adenovirus (CRAd) Ad5/3‐Cox2CRAd‐ΔE3‐ADP‐Luc replication after intratumoral injection into MiaPaCa‐2 xenografts. BALB/c nu/nu mice were inoculated with MiaPaCa‐2 cells, and when tumor nodules achieved a diameter of 6–10 mm, 1.0 × 1010 viral particles CRAd(Ad5/3‐Cox2CRAd‐ΔE3‐ADP‐Luc) were injected into tumors. The luciferase signal from the tumors was monitored from day 1.
