Table 1.
Comparative analysis of peripheral biomarkers between stroke patients measured on day 1 after admission and healthy controls
| Characteristics | Stroke patients (n=114) | Controls (n=40) | P |
|---|---|---|---|
| Age (years) | 71.7±10.2 | 67.9±13.9 | 0.121 |
| Gender (MF) | 65 (57.0)/49 (43.0) | 23 (57.5)/17 (42.5) | 0.958 |
| Parameters (pg/ml) at baseline | |||
| PDGF-AA | 1.08 (0.71, 2.14) | 0.76 (0.24, 1.70) | 0.097 |
| PDGF-AB/BB | 9.83 (5.11, 20.26) | 10.29 (4.16, 23.01) | 0.730 |
| PAI-1 | 150.08 (102.96, 185.90) | 145.78 (84.91, 187.36) | 0.548 |
| BDNF | 4.1 (2.73, 9.24) | 5.59 (2.57, 8.38) | 0.943 |
| RANTES | 17.01 (10.08, 31.28) | 38.28 (16.99, 53.21) | 0.004 |
| sICAM | 136.65 (110.26, 167.23) | 118.07 (55.88, 160.18) | 0.024 |
| sVCAM | 1537.89 (1280.62, 1856.16) | 1416.52 (1261.35, 1788.73) | 0.312 |
| NCAM | 370.00 (317.79, 430.80) | 416.72 (346.95, 477.54) | 0.019 |
| MPO | 539.93 (286.80, 1065.61) | 418.72 (311.81, 535.89) | 0.025 |
| Cathepsin D | 252.28 (210.79, 361.58) | 242.58 (180.85, 416.64) | 0.689 |
Data are expressed as mean±standard deviation, median and IQR (25th-75th percentile), or absolute (relative) frequencies; the estimated significance level obtained from the Mann-Whitney test. PDGF=Platelet-derived growth factor, PAI=plasminogen activator inhibitor, BDNF=brain-derived neurotrophic factor, RANTES=Regulated on Activation, Normal T Cell Expressed and Secreted, sICAM=soluble intercellular cell adhesion molecule, sVCAM=soluble vascular cell adhesion molecule, NCAM=neural cell adhesion molecule, MPO=myeloperoxidase; values in bold typeface denote statistical significance