Table 2.
Dynamic evolution of peripheral biomarkers, between days 1 and 5 after admission in ischemic stroke patients
| Parameters (pg/ml) | Day 1 after admission | Day 5 after admission | P |
|---|---|---|---|
| PDGF-AA | 1.04 (0.62, 2.21) | 1.10 (0.41, 3.13) | 0.288 |
| PDGF-AB/BB | 8.60 (4.71, 20.58) | 11.77 (4.76, 24.15) | 0.162 |
| PAI-1 | 151.23 (105.30, 185.96) | 152.32 (102.35, 222.39) | 0.154 |
| BDNF | 4.56 (2.47, 9.31) | 4.83 (2.44, 14.92) | 0.173 |
| RANTES | 16.43 (9.56, 35.99) | 14.38 (8.90, 19.57) | 0.016 |
| sICAM | 136.65 (108.69, 165.86) | 109.15 (66.12, 172.97) | 0.013 |
| sVCAM | 1578.38 (1294.69, 886.04) | 1470.26 (1220.17, 1686.31) | 0.001 |
| NCAM | 370.51 (317.63, 422.07) | 352.30 (328.47, 432.20) | 0.898 |
| MPO | 564.65 (299.85, 1160.86) | 780.08 (437.81, 1160.70) | 0.352 |
| Cathepsin D | 270.80 (212.08, 270.80) | 239.09 (199.05, 357.04) | 0.551 |
Data are expressed as median and IQR (25th and 75th percentile); the estimated significance level obtained from the Mann-Whitney test; values in bold typeface denote statistical significance. PDGF=Platelet-derived growth factor, PAI=plasminogen activator inhibitor, BDNF=brain-derived neurotrophic factor, RANTES=Regulated on Activation, Normal T Cell Expressed and Secreted, sICAM=soluble intercellular cell adhesion molecule, sVCAM=soluble vascular cell adhesion molecule, NCAM=neural cell adhesion molecule, MPO=myeloperoxidase; values in bold typeface denote statistical significance