Table 3.
The bivariate association between plasma biomarkers on day 1 and BI on day 5 after admission
| Parameters (pg/ml) | Stroke patients with BI >80, day 5 (n1=46) | Stroke patients with BI ≤80, day 5 (n2=68) | P |
|---|---|---|---|
| PDGF-AA | 1.13 (0.82, 2.50) | 0.90 (0.59, 1.50) | 0.010 |
| PDGF-AB/BB | 10.66 (6.80, 27.32) | 7.70 (3.14, 16.73) | 0.013 |
| PAI-1 | 153.51 (103.38, 182.52) | 131.05 (97.46, 190.96) | 0.677 |
| BDNF | 5.36 (3.50, 12.30) | 4.09 (1.92, 7.79) | 0.012 |
| RANTES | 19.41 (12.41, 42.33) | 12.84 (8.10, 22.58) | 0.010 |
| sICAM | 137.72 (118.74, 69.89) | 135.39 (102.68, 165.34) | 0.291 |
| sVCAM | 1517.43 (1249.57, 1730.93) | 1669.76 (1318.71, 2086.03) | 0.142 |
| NCAM | 361.14 (315.33, 412.78) | 396.32 (329.68, 451.07) | 0.134 |
| MPO | 505.73 (291.38, 938.11) | 581.23 (262.11, 1234.99) | 0.365 |
| Cathepsin D | 258.49 (215.58, 342.12) | 250.79 (205.34, 368.61) | 0.994 |
Data are expressed as median and IQR (25th and 75th percentile); the estimated significance level obtained from the Mann-Whitney test; values in bold typeface denote statistical significance. PDGF=Platelet-derived growth factor, PAI=plasminogen activator inhibitor, BDNF=brain-derived neurotrophic factor, RANTES=Regulated on Activation, Normal T Cell Expressed and Secreted, sICAM=soluble intercellular cell adhesion molecule, sVCAM=soluble vascular cell adhesion molecule, NCAM=neural cell adhesion molecule, MPO=myeloperoxidase; values in bold typeface denote statistical significance