Table 4.
Univariate and multivariate association of the studied parameters with functional dependence evaluated with BI on day 5
| Parameters (pg/ml) | Estimated value of COR (95% CI) | P | Estimated value of AORa (95% CI) | P |
|---|---|---|---|---|
| PDGF-AAb | 0.56 (0.39, 0.89) | 0.012 | 0.55 (0.32, 0.93) | 0.027 |
| PDGF-ABc | 0.70 (0.51, 0.97) | 0.034 | 0.64 (0.43, 0.96) | 0.030 |
| PAId | 0.87 (0.50, 1.52) | 0.620 | 0.79 (0.40, 1.57) | 0.503 |
| BDNFc | 0.50 (0.26, 0.97) | 0.039 | 0.42 (0.18, 0.97) | 0.042 |
| RANTESa | 0.86 (0.74, 1.01) | 0.058 | 0.85 (0.71, 1.02) | 0.072 |
| sICAMd | 0.81 (0.50, 1.32) | 0.402 | 0.84 (0.49, 1.44) | 0.532 |
| sVCAMd | 1.08 (0.99, 1.16) | 0.069 | 1.04 (0.93, 1.15) | 0.518 |
| NCAMd | 1.51 (0.95, 2.39) | 0.080 | 1.68 (0.90, 3.17) | 0.106 |
| MPOe | 1.17 (0.78, 1.76) | 0.456 | 1.17 (0.72, 1.91) | 0.532 |
| Cathepsind | 1.11 (0.88, 1.42) | 0.379 | 1.01 (0.74, 1.37) | 0.969 |
The estimated significance level obtained from univariate and multivariate logistic regression; aadjusting for age >70, gender, stroke history, TOAST classification, leucoaraiosis, NIHSS on admission; bper 1 unit increase of biomarker; cper 10 units increase of biomarker; dper 100 units increase of biomarker; eper 1000 units increase. 95% CI=Confidence interval (lower limit; upper limit); COR=crude odds ratio; AOR=adjusted odds ratio; PDGF=platelet-derived growth factor, PAI=plasminogen activator inhibitor, BDNF=brain-derived neurotrophic factor, RANTES=Regulated on Activation, Normal T Cell Expressed and Secreted, sICAM=soluble intercellular cell adhesion molecule, sVCAM=soluble vascular cell adhesion molecule, NCAM=neural cell adhesion molecule, MPO=myeloperoxidase; values in bold typeface denote statistical significance