TABLE 2.
P value | ||||||
---|---|---|---|---|---|---|
Characteristic | Baseline | Week 9 | Week 13 | Baseline vs. week 9 | Baseline vs. week 13 | Week 9 vs. week 13 |
Weight, kg | 104.0 ± 14.6 | 90.1 ± 11.6 | 90.0 ± 11.8 | <0.001 | <0.001 | 0.999 |
FM, kg | 43.3 ± 9.1 | 32.4 ± 8.6 | 31.4 ± 8.4 | <0.001 | <0.001 | <0.001 |
FFM, kg | 60.0 ± 10.9 | 57.6 ± 9.9 | 58.3 ± 10.1 | <0.001 | <0.001 | <0.001 |
ICW, L | 28.4 ± 5.9 | 27.2 ± 5.2 | 27.9 ± 9 | <0.001 | 0.791 | 0.126 |
RMRm, kcal/d | 1856 ± 249 | 1654 ± 204 | 1715 ± 238 | <0.001 | <0.001 | <0.001 |
RMRp, kcal/d | 1856 ± 221 | 1746 ± 193 | 1754 ± 197 | <0.001 | <0.001 | 0.005 |
RMRm−p, kcal/d | −0.01 ± 113 | −92 ± 110*** | −38 ± 124* |
Data presented as means ± SDs. Changes over time assessed with repeated-measures ANOVA, followed by post hoc comparisons between time points with Bonferroni adjustment. Asterisks denote significant differences between measured and predicted RMR at specific time points by paired sample t tests: *P = 0.011 and ***P < 0.001. FM, fat mass; FFM, fat-free mass; ICW, intracellular water; RMR, resting metabolic rate; RMRm, resting metabolic rate measured; RMRm−p, RMR measured minus RMR predicted; RMRp, resting metabolic rate predicted.