Table 2.

Apabetalone suppresses the expression of inflammatory genes in unstimulated monocytes obtained from DM2 + CVD patients and control subjects

^aGene expression is expressed as mean fold difference in response to 25 μM apabetalone treatment relative to vehicle (DMSO). ^bGenes significantly downregulated in response to 5 μM apabetalone. ^cGenes differentially sensitive to apabetalone treatment in DM2 + CVD versus control cells (also shown in Fig. 3a). Italics numbers indicate a fold change of > 30% with an adjusted p value < 0.05 (two-way repeated measures ANOVA)