Table 2. Total population and viability of the MG-63 cells analyzed from the samples cultured with the HIF inhibitor, YC-1.

Data are shown as mean±s.e.m. (n = 3).

YC-1 Concentration (μg/ml)	Monolayer Cell Culture (Initial Population: 2.40·106)		3D Spheroid Culture (Initial Population: 2.40·106)
	Total Population	Cell Viability	Total Population	Cell Viability
0 (Control)	13.81 ±0.07·106	98.5 ±0.4%	26.26±1.18·105	99.3±0.3%
20	6.40 ±0.23·106	92.7±2.6%	25.92±1.18·105	88.7±0.8%
40	2.25±0.12·106	79.0 ±2.2%	25.82±1.17·105	78.4±2.6%
60	1.34 ±0.13·106	40.8 ±1.9%	25.07±0.85·105	51.9±4.5%