Fig 8. Influence of baseline severity on outcome variability.
Estimated VR of antidepressants versus placebo as a function of baseline severity on the HAMD17-scale as determined by the REMR. Depicted are the mean estimates and 95% HDIs for three different values of the response ratio (mean response active versus mean response placebo). The meta-analytic mean of RR is around 1.22 in the Cipriani data set.