Table 3.
Demographic and clinical outcomes of asthma and non-asthma patients stratified by obesity.
| Characteristics | Non-obese |
Obese |
|||||
|---|---|---|---|---|---|---|---|
| Non-asthma (n = 197) | Asthma (n = 18) | P value | Non-asthma (n = 233) | Asthma (n = 54) | P-value | ||
| Age | Mean ± SD | 65.02 ± 16.32 | 59.50 ± 18.30 | 0.18 | 58.28 ± 14.38 | 57.09 ± 13.03 | 0.58 |
| Sex | Female | 80 (41) | 8 (44.4) | 0.81 | 135 (57.9) | 38 (71.7) | 0.09 |
| Male | 115 (59) | 10 (55.6) | 98 (42.1) | 15 (28.3) | |||
| Race | African American | 136 (69) | 15 (83.3) | 0.07 | 177 (76) | 47 (87) | 0.12 |
| White | 43 (21.8) | 0 (0) | 38 (16.3) | 3 (5.6) | |||
| Not Reported | 18 (9.1) | 3 (16.7) | 18 (7.7) | 4 (7.4) | |||
| Smoking | Active smokers | 20 (10.2) | 2 (11.1) | 0.98 | 17 (7.3) | 6 (11.1) | 0.48 |
| Severity | qSOFA | 0.65 ± 0.71 | 0.67 ± 0.65 | 0.95 | 0.71 ± 0.69 | 0.95 ± 0.74 | 0.05 |
| CURB65 | 1.63 ± 1.16 | 1.58 ± 1.31 | 0.90 | 1.33 ± 1.08 | 1.25 ± 1.17 | 0.69 | |
| PF ratio | 269.47 ± 118.89 | 207.67 ± 67.00 | 0.39 | 229.33 ± 104.62 | 248.14 ± 133.52 | 0.67 | |
| Respiratory rate | 20.96 ± 6.98 | 20.94 ± 5.04 | 0.99 | 22.48 ± 7.33 | 25.21 ± 7.32 | 0.022 | |
| Lab testing | Ferritin | 802.44 ± 771.40 | 3192.06 ± 5897.4 | 0.012 | 1121.2 ± 2379.5 | 923.37 ± 767.81 | 0.79 |
| NLR | 8.37 ± 8.81 | 6.10 ± 4.33 | 0.34 | 7.61 ± 11.68 | 6.69 ± 4.60 | 0.61 | |
| Procedures | Intubation | 37 (19.2) | 6 (33.3) | 0.22 | 81 (34.9) | 23 (42.6) | 0.29 |
| Extubation | 22 (59.5) | 5 (83.3) | 0.39 | 54 (66.7) | 20 (87) | 0.06 | |
| Re-intubation | 3 (13.6) | 2 (40) | 0.22 | 7 (13) | 2 (10) | 0.73 | |
| Mechanical ventilation | 35 (39.8) | 5 (62.5) | 0.27 | 74 (61.2) | 24 (72.7) | 0.22 | |
| ICU admission | 42 (21.4) | 4 (22.2) | 0.93 | 77 (33.2) | 26 (48.1) | 0.042 | |
| Days of events | Intubation days | 2.45 ± 3.30 | 2.00 ± 3.37 | 0.80 | 1.38 ± 2.07 | 2.73 ± 3.63 | 0.032 |
| Ventilation days | 0.91 ± 2.85 | 0.63 ± 1.77 | 0.78 | 2.88 ± 5.23 | 2.11 ± 2.86 | 0.46 | |
| ICU LOS | 8.11 ± 7.17 | 7.50 ± 4.95 | 0.91 | 9.00 ± 6.84 | 7.50 ± 5.02 | 0.54 | |
| Total LOS | 11.72 ± 11.22 | 17.79 ± 10.82 | 0.05 | 11.34 ± 10.06 | 14.39 ± 12.91 | 0.08 | |
| Complications | None | 107 (54.3) | 9 (50) | 0.81 | 109 (46.8) | 21 (38.9) | 0.36 |
| One or more | 90 (45.7) | 9 (50) | 124 (53.2) | 33 (61.1) | |||
| Types of complications | ARDS | 45 (22.8) | 5 (27.8) | 0.57 | 88 (37.8) | 22 (40.7) | 0.69 |
| RF/AKI | 44 (22.3) | 3 (16.7) | 0.77 | 56 (24) | 13 (24.1) | 1.00 | |
| Sepsis | 28 (14.2) | 0 (0) | 0.14 | 33 (14.2) | 14 (25.9) | 0.042 | |
| Bacteremia | 17 (8.6) | 0 (0) | 0.37 | 11 (4.7) | 6 (11.1) | 0.07 | |
| Mortality | Discharged alive | 171 (89.1) | 17 (94.4) | 0.70 | 195 (84.4) | 48 (88.9) | 0.52 |
| Died | 21 (10.9) | 1 (5.6) | 36 (15.6) | 6 (11.1) | |||
PF ratio: PaO2: FiO2 ratio, ICU: intensive care unit, LOS: length of stay, ARDS: acute respiratory distress syndrome, RF/AKI: renal failure/acute kidney injury.