TABLE 4.
Distribution of virulence genes (other than F4- and F18-encoding fimbria) among the 90 ETEC isolates
| Function and gene | Total no. (%) of isolates | No. (%) of isolates of each fimbrial typea
|
P value | ORb (95% CI) | |
|---|---|---|---|---|---|
| F4 | F18 | ||||
| Toxins | |||||
| astA | 77 (85.6) | 69 (100) | 8 (38.1) | <0.0001 | ∞ (25.71–∞) |
| ltcA | 82 (91.1) | 69 (100) | 13 (62) | <0.0001 | ∞ (9.402–∞ |
| sta | 21 (23.3) | 13 (18.8) | 8 (38.1) | 0.0820 | |
| stb | 85 (94.4) | 69 (100) | 16 (76.2) | 0.0005 | ∞ (5.465–∞) |
| Fimbriae | |||||
| lpfA | 15 (16.7) | 2 (2.9) | 13 (61.9) | <0.0001 | 0.01837 (0.003635–0.08) |
| fasA | 2 (2.2) | 2 (2.9) | 0 | >0.9999 | |
| Adhesion | |||||
| iha | 77 (85.6) | 57 (82.6) | 20 (95.2) | 0.2854 | |
| air | 4 (4.4) | 0 | 4 (19) | 0.0023 | 0 (0.0–0.02885) |
| Colicin | |||||
| cba | 33 (36.7) | 33 (47.8) | 0 | <0.0001 | ∞ (4.748–∞) |
| cma | 47 (52.2) | 42 (60.9) | 5 (23.8) | 0.0053 | 4.978 (1.631–13.29) |
| celB | 10 (11.1) | 8 (11.6) | 2 (9.5) | >0.9999 | |
| Microcin | |||||
| mchB | 9 (10) | 9 (13) | 0 | 0.1096 | |
| mchC | 9 (10) | 9 (13) | 0 | 0.1096 | |
| mchF | 9 (10) | 9 (13) | 0 | 0.1096 | |
| mcmA | 9 (10) | 9 (13) | 0 | 0.1096 | |
| Others | |||||
| capU | 55 (61.1) | 54 (78.3) | 1 (4.8) | <0.0001 | 72 (11.75–759.7) |
| gad | 40 (44.4) | 35 (50.7) | 5 (23.8) | 0.0439 | 3.294 (1.09–8.811) |
| sepA | 10 (11.1) | 10 (14.5) | 0 | 0.1088 | |
| iss | 20 (22.2) | 1 (1.4) | 19 (90.5) | <0.0001 | 0.001548 (0.0001506–0.0) |
| eilA | 5 (5.6) | 0 | 5 (23.8) | 0.0005 | 0 (0.0–0.1830) |
a
Percentage is estimated based on the total number of strains associated with each fimbria type. Significant differences (P < 0.05) are indicated in boldface.
b
The odds ratio (OR) is indicated when the P value is <0.05; CI, confidence interval; ∞, infinity.