Gene arrangements of TK2109 and TK2248 homologs in seven archaea. Some archaeal organisms which possess TK2109 homolog, TK2248 homolog, and biotin or lipoate-protein ligase are shown. Vertical stripe, horizontal stripe, gray, and black arrowed boxes represent TK2109 homolog, TK2248 homolog, biotin or lipoate-protein ligase, and H-protein genes, respectively. Genes overlapping any of the above four genes, along with some neighboring genes, are shown with white arrowed boxes.