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. 1999 Sep;20(8):1491–1499.

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fig 3. — Patient N.O.: 15-year-old girl with 10-month history of Schilder's MS variant.

A–E, Unusual bihemispheric callosal plaque shows a mixed pattern with rim enhancement on T1-weighted contrast-enhanced (A) and T2-weighted (B) images. Diffusion-weighted image shows moderate hyperintensity, caused by T2 shine through in lesion center, with hyperintense rim (C). Calculated ADC map (not shown) revealed increased diffusibility in lesion center with slight decrease in rim. Calculated maps of FA (D) and eccentricity (E) show marked tendency toward isotropy in lesion center, with minimal anisotropic reduction in rim. ADC values: NAWM, 0.00068; acute plaque center, 0.00155; acute plaque rim, 0.00072. FA values: NAWM, 0.568; acute plaque center, 0.176; acute plaque rim, 0.312.