fig 3.

Patient 10: initial and follow-up examinations.

A, 2 hours 50 minutes after onset.

B, 30 hours after onset, during therapy with heparin. The patient suffered from a large infarct in the left hemisphere with global aphasia and right hemiparesis. The first native CT scan (A) reveals only discrete cortical hypodensity and effacement of cortical sulci in the ischemic hemisphere. In contrast, the time-to-peak map clearly shows the extent of the affected brain area, which corresponds strongly to the hypodensity seen on the CT scan in the follow-up study (B). The time-to-peak map shows tissue reperfusion 30 hours later. A large MCA infarction developed despite recanalization.