A and B, Serial MR follow-up of a nodular-enhancing lesion in the right frontal white matter and a nonenhancing hypointense lesion (arrow, A) in the left frontal white matter (arrowhead, A) on contrast-enhanced T1-weighted images (550/14) at baseline (A) and 12 months later (B). The nodular-enhancing lesion has become completely isointense on the 12-month image. In this lesion, the MTR increased from 34% on the baseline image to 39% on the 12-month image. The nonenhancing lesion in the left frontal lobe shows no significant change on the serial MR follow-up images, and the MTR values remained between 24% on the baseline image and 26% on the 12-month image.