Table 3. Patient characteristics associated with higher risk of cancer recurrence and death.
Patient characteristics | Hazard ratio (95% CI), P value | |
---|---|---|
Cancer recurrence (n=326) | Death of any cause (n=326) | |
Demographics | ||
Age at diagnosis (65+ vs. younger) | 0.9 (0.5, 1.4), 0.2466 | 1.2 (0.9, 1.8), 0.2362 |
Sex (male vs. female) | 0.7 (0.5, 1.2), 0.2242 | 1.0 (0.7, 1.4), 0.9362 |
Race | ||
Caucasian vs. Asian | 1.6 (0.9, 2.9), 0.1255 | 1.6 (1.1, 2.5), 0.0215 |
Caucasian vs. Hispanic | 0.8 (0.4, 1.4), 0.3574 | 1.0 (0.6, 1.7), 0.8353 |
Clinical characteristics | ||
Smoking/alcohol (yes vs. no) | 1.4 (0.9, 2.2), 0.1586 | 1.0 (0.7, 1.5), 0.8800 |
Significant weight loss (yes vs. no/unknown) | 3.0 (2.0, 4.7), <0.0001 | 2.4 (1.7, 3.3), <0.0001 |
History of cancer (yes vs. no) | 1.5 (0.8, 2.7), 0.1954 | 1.6 (1.0, 2.5), 0.0604 |
Charlson comorbidity (high vs. low burden) | 0.7 (0.3, 1.3), 0.2681 | 1.6 (1.0, 2.5), 0.0653 |
Tumor characteristics | ||
Tumor size (large vs. small/med/unknown) | 1.1 (0.6, 2.0), 0.7230 | 1.3 (0.8, 1.5), 0.2148 |
Histology (diffuse vs. intestinal/mixed/unknown) | 1.2 (0.7, 2.1), 0.4104 | 1.0 (0.7, 1.5), 0.8621 |
Pathological stage (loco-regional vs. localized) | 3.0 (1.9, 4.7), <0.0001 | 2.7 (1.9, 3.9), <0.0001 |