Table IV.
Relation of clinical and admission laboratory markers for invasive mechanical ventilation
| Variable | Univariable |
Multivariable |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age | 1.00 | 0.99-1.02 | .84 | – | – | – |
| Male sex | 0.94 | 0.60-1.47 | .79 | – | – | – |
| Hypertension | 1.05 | 0.69-1.60 | .81 | – | – | – |
| Hyperlipidemia | 0.87 | 0.57-1.32 | .52 | – | – | – |
| Diabetes mellitus | 0.97 | 0.64-1.47 | .88 | – | – | – |
| Active tobacco use | 2.47 | 0.98-6.20 | .054 | 2.06 | 0.72-5.87 | .18 |
| Coronary artery disease | 0.95 | 0.50-1.79 | .87 | – | – | – |
| Previous DVT or PE | 1.33 | 0.53-3.30 | .54 | – | – | – |
| Respiratory disease | 1.28 | 0.68-2.41 | .45 | – | – | – |
| Active malignancy | 1.60 | 0.64-3.97 | .31 | – | – | – |
| DIC | 1.75 | 0.80-3.80 | .16 | – | – | – |
| Admission laboratory markers | ||||||
| D-dimer, per 100-U increase | 1.011 | 1.004-1.017 | .001 | 1.010 | 1.001-1.020 | .04 |
| Fibrinogen, per 100-U increase | 1.151 | 1.000-1.324 | .049 | – | – | – |
| PT | 1.027 | 0.984-1.071 | .23 | – | – | – |
| PTT | 1.007 | 1.001-1.014 | .028 | 1.004 | 0.99-1.02 | .56 |
| Platelet count, per 1000-U increase | 2.951 | 0.245-35.630 | .39 | – | – | – |
| CRP, per 10-U increase | 1.000 | 0.980-1.020 | .90 | – | – | – |
| hs-Troponin T | 1.000 | 0.999-1.000 | .51 | – | – | – |
CI, Confidence interval; CRP, C-reactive protein; DIC, disseminated intravascular coagulation; DVT, deep vein thrombosis; HR, hazard ratio; hs, high sensitivity; PE, pulmonary embolism; PT, prothrombin time; PTT, partial thromboplastin time.
Boldface P values represent statistical significance.