Table V.
Relation of clinical and admission laboratory markers for death
| Variable | Univariable |
Multivariable |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age | 1.04 | 1.01-1.07 | .01 | 1.04 | 1.00-1.07 | .04 |
| Male sex | 0.99 | 0.40-2.45 | .99 | – | – | – |
| Hypertension | 1.64 | 0.71-3.80 | .25 | – | – | – |
| Hyperlipidemia | 1.11 | 0.49-2.54 | .80 | – | – | – |
| Diabetes | 1.17 | 0.51-2.67 | .71 | – | – | – |
| Active tobacco use | 0.00 | 0.00-Inf | 1.00 | – | – | – |
| Coronary artery disease | 1.88 | 0.73-4.81 | .19 | – | – | – |
| Previous DVT or PE | 1.64 | 0.38-7.02 | .51 | – | – | – |
| Respiratory disease | 0.67 | 0.19-2.40 | .54 | – | – | – |
| Active malignancy | 6.46 | 2.37-17.65 | .0003 | 4.39 | 1.39-13.91 | .01 |
| Venous thrombosis | 1.46 | 0.64-3.33 | .37 | – | – | – |
| Invasive mechanical ventilation | 0.40 | 0.12-1.32 | .13 | – | – | – |
| DIC | 4.36 | 1.38-13.74 | .01 | 4.81 | 1.76-13.10 | .002 |
| Admission laboratory markers | ||||||
| D-dimer, per 100-U increase | 1.014 | 1.002-1.025 | .02 | 1.016 | 1.003-1.029 | .02 |
| Fibrinogen, per 100-U increase | 1.185 | 0.756-1.859 | .46 | – | – | – |
| PT | 1.069 | 0.968-1.180 | .19 | – | – | – |
| PTT | 0.991 | 0.970-1.013 | .42 | – | – | – |
| Platelet count, per 1000-U increase | 3.558 | 0.030-4.275 | .60 | – | – | – |
| CRP | 1.030 | 0.998-1.070 | .07 | – | – | – |
| hs-Troponin T | 1.000 | 0.997-1.002 | .85 | – | – | – |
CI, Confidence interval; CRP, C-reactive protein; DIC, disseminated intravascular coagulation; DVT, deep vein thrombosis; HR, hazard ratio; hs, high sensitivity; PE, pulmonary embolism; PT, prothrombin time; PTT, partial thromboplastin time.
Boldface P values represent statistical significance.