Table 4.
Results for SNPs that were genome-wide significant in the conditional analysis and have larger estimated conditional effect sizes than in the original GWAS
| Disorder | SNP | CHR | Position | A1 | Adjusted beta | SE Adjusted beta | Unadjusted beta | SE Unadjusted beta | Adjusted p-value | Unadjusted p-value | nearestGene |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SCZ | rs3764002 | 12 | 108618630 | C | 0.083 | 0.012 | 0.054 | 0.011 | 1.94E-12 | 6.05E-07 | WSCD2 |
| SCZ | rs6095357 | 20 | 47523865 | A | −0.069 | 0.011 | −0.048 | 0.010 | 1.17E-10 | 1.21E-06 | ARFGEF2 |
| SCZ | rs7790864 | 7 | 28478625 | A | −0.062 | 0.011 | −0.044 | 0.010 | 6.33E-09 | 7.18E-06 | CREB5 |
| SCZ | rs1054972 | 19 | 1852582 | A | 0.076 | 0.013 | 0.053 | 0.012 | 6.42E-09 | 1.32E-05 | KLF16 |
| SCZ | rs2867673 | 7 | 71752652 | T | 0.060 | 0.010 | 0.049 | 0.010 | 9.44E-09 | 4.11E-07 | CALN1 |
| SCZ | rs6564668 | 16 | 79457393 | C | −0.060 | 0.010 | −0.038 | 0.010 | 1.05E-08 | 7.94E-05 | RP11-467I7.1 |
| SCZ | rs11922765 | 3 | 95047279 | G | −0.060 | 0.010 | −0.044 | 0.010 | 1.22E-08 | 4.36E-06 | RPS18P6 |
| SCZ | rs2973038 | 5 | 37833781 | C | 0.066 | 0.012 | 0.051 | 0.011 | 1.28E-08 | 1.72E-06 | GDNF |
| SCZ | rs10903945 | 10 | 363275 | C | 0.057 | 0.010 | 0.040 | 0.010 | 3.13E-08 | 3.30E-05 | DIP2C |
| SCZ | rs10282935 | 8 | 38703797 | A | 0.058 | 0.011 | 0.041 | 0.010 | 3.97E-08 | 3.17E-05 | TACC1 |
| SCZ | rs6701877 | 1 | 174015259 | G | −0.096 | 0.014 | −0.073 | 0.013 | 1.47E-11 | 2.37E-08 | RP11-160H22.3 |
| SCZ | rs7372313 | 3 | 135872958 | G | −0.069 | 0.010 | −0.062 | 0.010 | 4.26E-11 | 1.54E-10 | MSL2 |
| SCZ | rs1765142 | 11 | 30378559 | C | 0.065 | 0.011 | 0.058 | 0.010 | 1.54E-09 | 1.13E-08 | ARL14EP |
| SCZ | rs55646993 | 7 | 105017864 | G | −0.062 | 0.010 | −0.053 | 0.010 | 2.23E-09 | 3.83E-08 | SRPK2 |
| SCZ | rs150437760 | 14 | 59981768 | A | 0.131 | 0.024 | 0.121 | 0.022 | 3.71E-08 | 4.58E-08 | CCDC175 |
| BIP | rs12554512 | 9 | 23352293 | T | −0.083 | 0.014 | −0.066 | 0.014 | 1.55E-09 | 1.28E-06 | ELAVL2 |
| BIP | rs6891181 | 5 | 80849101 | T | −0.081 | 0.014 | −0.075 | 0.014 | 1.49E-08 | 1.27E-07 | SSBP2 |
| BIP | rs12268910 | 10 | 111878510 | T | −0.097 | 0.018 | −0.091 | 0.018 | 3.29E-08 | 2.73E-07 | ADD3 |
| MD | rs11697370 | 20 | 47731767 | T | −0.031 | 0.005 | −0.023 | 0.005 | 3.31E-09 | 3.53E-06 | STAU1 |
| MD | rs27732 | 5 | 87992576 | A | 0.034 | 0.005 | 0.031 | 0.005 | 1.22E-11 | 1.87E-10 | MEF2C |
| MD | rs1806153 | 11 | 31850105 | T | 0.037 | 0.006 | 0.036 | 0.006 | 8.78E-10 | 1.18E-09 | RCN1 |
| MD | rs1354115 | 9 | 2983774 | A | 0.029 | 0.005 | 0.028 | 0.005 | 1.72E-08 | 2.37E-08 | CARM1P1 |
| MD | rs301799 | 1 | 8489302 | T | −0.028 | 0.005 | −0.026 | 0.005 | 2.49E-08 | 4.68E-08 | RERE |
| ADHD | rs78648104 | 6 | 50683009 | T | 0.136 | 0.023 | 0.124 | 0.025 | 4.31E-09 | 3.60E-07 | TFAP2D |
| ADHD | rs2244336 | 10 | 8831827 | C | 0.071 | 0.013 | 0.069 | 0.014 | 3.81E-08 | 3.67E-07 | ENSG00000270234 |
| ADHD | rs12410444 | 1 | 44188719 | A | 0.107 | 0.014 | 0.106 | 0.015 | 4.23E-15 | 3.85E-13 | ST3GAL3 |
| ADHD | rs13023832 | 2 | 215219808 | A | 0.133 | 0.020 | 0.117 | 0.021 | 1.23E-11 | 1.62E-08 | SPAG16 |
| ADHD | rs281320 | 15 | 47769424 | T | −0.080 | 0.013 | −0.074 | 0.013 | 1.84E-10 | 3.14E-08 | SEMA6D |
| AUT | rs10099100 | 8 | 10576775 | C | 0.084 | 0.014 | 0.084 | 0.015 | 1.20E-09 | 1.07E-08 | SOX7 |